Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 19th World Dermatology Congress Tokyo, Japan.

Day 1 :

Keynote Forum

Saad Sami AlSogair

Managing Director, Elite Derma Care Center, Saudi Arabia

Keynote: Anti-Aging Potentials of Methylene Blue for Human Skin

Time : 09:00AM-10:00AM

Conference Series World Dermatology 2018 International Conference Keynote Speaker Saad Sami AlSogair photo
Biography:

Dr. Saad Sami Al Sogair is a Board certified Dermatologist and faculty member of the American Aesthetic Association. He is also an active speaking member of multiple international Aesthetic and Anti-Aging societies and academies. Including the Saudi Society of Dermatology and Dermatologic Surgery, the Swiss Academy of Cosmetic Dermatology & Aesthetic Medicine, the American Academy of Aesthetic Medicine and the American Academy of Anti-Aging Medicine. Dr. Sogair has numerous published articles translated into many languages including Italian and Portuguese. His findings in Aesthetic Dermatology were described by Reuters as “breakthrough.”

 

 

Abstract:

Skin is the largest and the most visible organ of the human body. Aged skin is biologically characterized by the flattening of the dermal-epidermal junction, general atrophy of the extracellular matrix (ECM) and disorganized and reduced collagen and elastin. Skin aging can be delayed by external application to suppress production of free radicals or to neutralize excess free radicals. Methylene blue is a century-old drug has potent antibiotic and antioxidant properties and has the ability to suppress production of superoxide radicals. It acts as an alternative receptor of xanthine oxide electrons and has received increased attention due to its usefulness in treating mitochondrial dysfunction. MB at nanomolar concentration has been found to be potent in scavenging free radicals and stimulate cell proliferation in both young and old dermal fibroblasts. MB treatment on 3D reconstructed skin models provides strong evidence of its potential for improving skin viability, increasing skin hydration and thickness, promoting skin elastin and collagen synthesis, and protecting the skin matrix through the inhibition of enzymatic degradation by MMP. Altogether, this presentation suggests that MB can be a promising agent for use in anti-aging cosmetics.

 

Keynote Forum

Dr. Andrea Merino-Ruisánchez

Dorrington Medical Associates, Houston, Texas, USA

Keynote: Ulcerated Basosquamous Cell Carcinoma on Shoulder Case Report and Review of Literature

Time : 10:00AM-11:00AM

Conference Series World Dermatology 2018 International Conference Keynote Speaker Dr. Andrea Merino-Ruisánchez photo
Biography:

Andrea Merino-Ruisanchez is a physician from the Universidad Popular Autonoma del Estado de Puebla (UPAEP) in Mexico. Following a clinical Psychology diplomate, she developed a keen interest in dermatology. She has presented internationally data on the prevalence of dermatologic and ophthalmic manifestations in systemic lupus erythematous. She is certified in “Good Clinical Practices” by the NIDA Clinical trials network.

 

Abstract:

Basosquamous cell carcinoma (BSC) is a rare, and potentially aggressive, skin neoplasm with features of both basal cell carcinoma (BCC), and squamous cell carcinoma (SCC) with a transition zone and a non-specific clinical presentation. We recently saw a 57-year-old gentleman who presented ulcerated BSC on the right shoulder reaching the acromion with a polymicrobial infection. Microscopical analysis showed a transition zone between BCC and SCC. A Periodic acid-Shiff-Fungus special stain was negative for fungal organisms. BSC represents less that 5% of all non-melanoma skin tumors. The incidence is less than 2% but the true incidence may be higher due to rarity and difficulty of diagnosis. This neoplasm is most commonly found on head and neck on 82-97% of cases. In 2005, the World Health Organization defined BSC as a term used to describe BCC that is associated with squamous differentiation. Prompt recognition of BSC is important in order to aggressively treat and predict the prognosis.

 

 

  • Medical Dermatology | Dermatology types | Dermatological Diseases | Skin Grafting |Hair transplantation|Skin Rejuvenation and Resurfacing
Location: Radisson Narita
Speaker

Chair

Andrea Merino-Ruisanchez

Universidad Popular Autonoma del Estado de Puebla (UPAEP), Puebla, Mexico

Co-Chair

Roberto Dell Avanzato

MD Medical Department of Espace Chenot Health Wellness & Spa, Italy

Session Introduction

Roberto Dell’Avanzato

Managing Director of Medical Department of Espace Chenot Health Wellness & Spa

Title: A revolutionary mini-invasive treatment for cellulite blemishes: 15 months of initial experience
Biography:

Roberto Dell’Avanzato is the  Managing Director of Medical Department of Espace Chenot Health Wellness & Spa

Abstract:

A new procedure that represents the only FDA-cleared minimally invasive treatment clinically proven to improve the cellulite blemishes for nearly four years in only one session.The procedure treated successfully the primary structural cause of cellulite blemishes in all the 50 patients. Patient satisfaction was 87% at T90 in 50 patients 95% at T180 in 50 patients, 97% at 12 months in 13 patients and 100% at 15 months in 3 patients. Transient treatment-related adverse events were mild in severity and the most common side effects reported were soreness and bruising. Among 50 patients, 95% had bruising at T7, 23% at T14 and no patient had bruising at T30. Soreness is reported in 100% of patients at T7, 19% at T14, 4% at T30 and 0% at T90. Global Aesthetic Improvement Scale and Visual Analog Scale are also reported. This revolutionary FDA-cleared procedure for the cellulite puckering, combines a proven approach with an innovative technology to treat the primary structural cause of cellulite blemishes in posterior thighs and buttocks. This study confirms his safety, and efficacy with vacuum-assisted precise tissue release for the treatment of cellulite, which is also strengthened by patients satisfaction.

 

Biography:

Theodore D. Zaki, is the  Managing Director of Yale University School of Medicine, USA

Abstract:

The patient is a 75-year-old woman with seropositive RA with polyarthropathy, who had recently started adalimumab presented with a diffuse skin eruption. She had been previously treated with tocilizumab (4mg/kg monthly), methotrexate (10 mg weekly), and prednisone (5 mg weekly), with declining therapeutic effect. She was to undergo treatment with adalimumab (40 mg / 2 weeks). The patient reported that she administered a first adalimumab injection in the right lower abdominal quadrant two weeks prior to dermatologic evaluation. One day prior to dermatologic evaluation, she noted a round rash at the injection site and then overnight developed multiple skin lesions. She reported pruritus but otherwise felt well. Of note, she had taken 2 g of amoxicillin four days prior for a dental procedure. She had no additional medications. Physical examination revealed an 8 cm round erythematous patch with central, dusky hyperpigmentation over the right abdomen. There were numerous 3-8 mm urticarial macules and papules scattered over the legs, trunk, and arms, some with dusky centers. Urticarial patches were present on the palms. Oral mucosa and conjunctivae were unremarkable.A punch biopsy of the abdominal injection site showed perivascular lymphocytes and eosinophils, indicative of a drug eruption. Punch biopsy of an urticarial papule on the left thigh showed LCV, characterized by fibrinoid degeneration of small blood vessels and a mixed infiltrate, with abundant neutrophils and prominent nuclear dust. Various adverse events have been reported in clinical trials of subcutaneous TNF-α inhibitors, most commonly ISRs. ISR, by definition, includes any of: erythema, pruritus, hemorrhage, pain, or swelling at the site of injection. LCV is a small vessel vasculitis involving dermal postcapillary venules. Drugs cause roughly 10% of LCV, which generally manifest between 7 and 21 days following treatment. Numerous studies have associated anti-TNF-α therapy with vasculitis,7-10 most commonly cutaneous vasculitis (most prevalent in patients with RA).8 During RA clinical trials using adalimumab, the incidence of LCV was 0.01 events per 100 person-years of exposure.4 The pathogenesis of anti-TNF-α associated vasculitis remains unclear. One hypothesis is that anti-drug host antibodies initiate an immune-complex mediated hypersensitivity reaction. Another theory suggests that TNF-α antagonists induce a switch from the predominant T helper 1 (Th1) profile of RA to a Th2 response.The skin lesions began at the injection site and subsequently spread. Given the injection site localization and the time course, adalimumab was presumed to be causative. It is possible that amoxicillin could also have caused the diffuse eruption. Our patient was successfully treated with discontinuation of adalimumab and initiation of corticosteroid therapy, with antihistamines as needed.

Lilia Rabenok

Medicina Cirugia Estetica Ambulatoria, Mexico

Title: A clinical case of treatment of Gynecomasty
Biography:

Lilia Rabenok is working in Medicina Cirugia Estetica Ambulatoria in Mexico.

Abstract:

 One patient with Gynecomasty was examined and using surgical treatment in combinating with liposuccion  of  breath and  body in out-patient clinic.  After the surgical treatmen we used a radiofrecuency field twice a week during 4 weeks. Good results of medical treatment without complications were observed in this case. We conclude that using surgical treatment and radiofrecuency field after the surgery is effective in complex treatment of gynecomasty in out-patient clinic.

 

Moudad Alamatori

Ministry of health Swedaa Department Syria and chief of AIDS program

Title: Cutaneous tuberculosis study case
Biography:

Dr Moudad Alamatori  Damascus University is specialized in  Dermatology and Venerology. He is having experience in Swaidaa government hospital , Swaidaa, Syria. He is the Ministry of health Swedaa Department , Swaidaa , Syria and chief of AIDS program. He is having own Private Specific clinic, Swedaa, Syria.

 

Abstract:

M.H 15 year old Female Sweda Syria and the complain began seven years ago with chronic ulcers with facial erythma and upper lip enlargement.A well demarcated, slightly elevated infiltrated plaque with scarring in the centerThe case has increased until total tissues loss [Pick Nose]Oral, Nasal mucosae are involved small, soft gray, ulcers, pink papules bleed easily.Pressure with a glass slide shows small yellowish-brown spots. Apple-jelly.Enlargement region lymph nodes.The diagnosed was cutaneous Leishmaniasis positive test.The patient had been treated with glucantim for one year no improvement has been occurred.Plastic surgery has been made after one year with good result.

 

Biography:

Dr.Yun Ho Lee is resident in  Kangbuk Samsung  Hospital

Abstract:

27 patients (13 males and 14 females, mean age 46.7 ± 15.7 years) were analyzed. A total of 151 nails, consisting of 105 finger nails and 46 toe nails, were treated with a 1064 nm PSNY. The mean treatment session was 7.5 ± 4.2. After receiving a 1064nm PSNY laser therapy, 16 patients (59 %) showed more than 50 % improvement. There were no serious adverse events associated with the treatment during follow-up period. Idiopathic onychodystrophy successfully treated with a 1064nm PSNY laser. This device offers a new and potentially therapeutic modality for the patients with idiopathic onychodystrophy.

 

Jae Yun Lim

Resident in Kangbuk Samsung Hospital, South Korea

Title: Squamous Cell Carcinoma Presenting as Cellulitis
Biography:

Dr.Jae Yun Lim  is  resident in  Kangbuk Samsung Hospital.

 

Abstract:

Skin squamous cell carcinoma (SCC) presents as papules or plaques with erythematous or pigmented appearance that may ulcerate the skin. There are few reports from literature that SCC presents as skin cellulitis. By knowing the unusual presentations of SCC and diagnosing SCC in the early stage, advanced metastasis of the disease can be prevented and good prognosis with modest mean survival rate can be achieved.A 73-year-old female presented with diffuse erythematous patches with heating sense on left thigh. The patient received wide excision of well-differentiated squamous cell carcinoma of left shin 4 years ago. The patient was treated as an outpatient for cellulitis with antibiotics, which produced almost complete improvement after 6 months. However, multiple tiny erythematous papules with diffuse erythematous patches on left thigh were persistent after 6 months of antibiotics treatment. Punch biopsy of the lesion confirmed well-differentiated, microinvasive squamous cell carcinoma. The histologic examination of the lesion showed scattered atypical squamoid and basaloid tumor nests in the upper and deep dermal layer. Herein, we report a case with squamous cell carcinoma presenting as cellulitis.

 

Junghwa Yang

Resident in Kangbuk Samsung Hospital, South Korea

Title: Scalp White Piedra caused by Rhodotorula species
Biography:

Dr. Junghwa Yang  is resident in  Kangbuk Samsung  Hospital.

 

Abstract:

White piedra is a superficial mycotic infection of the hair shaft, characterized by small, firm, irregular gritty nodules. This asymptomatic infection, also known as tinea nodosa and trichomycosis nodularis, is mainly caused by basidiomycetous yeasts in the genus Trichosporon. But rarely has this disease due to other fungi infection been reported and no case of white piedra in Korean was documented so far.

A 22-year-old man presented with palpable translucent to white nodules along the left temporal scalp hair. He denied other symptoms like scalp irritation or pruritus, but complained the affected hairs became brittle and easily broke at points of attached nodules. On the contrary, the adjacent scalp skin was not affected.

For the diagnosis, fungus culture from the affected hair on Sabouraud agar was performed and it revealed distinctive orange to red colonies, which were diagnostic of Rhodotorulla species. The patient was treated with oral itraconazole and isoconazole cream, and his symptom was clinically improved after a month with significant decrement of the concretions and brittle hairs.Thus, we will introduce this patient as a rare case of white piedra caused by Rhodotorula species.

 

Biography:

Dr. Hyeon Jeong Park   is resident in  Kangbuk Samsung  Hospital.

 

Abstract:

As many surgical operations have been replaced by laparoscopic surgery, the number of umbilical keloid patients is gradually increasing. Generally, as keloids are painful in the disease itself, clinical differentiation with secondary infection could be difficult. If a thick keloid is formed, it may be a hard problem to confirm the fluctuation and heat sensation in the physical examination. For these reasons, rapid and appropriate surgical intervention can be delayed in numerous umbilical keloid patients.

We experienced three cases of secondary keloid infection in our hospital. In two middle-aged women with tenderness of the keloid, an inflammatory epidermoid cyst was identified by incisional biopsy. Pus from the both patients was sent for microbiological examination, but any significant bacteria growth that might be a pathogenicity factor was not found. Both patients were treated by empirical antibiotics and pus drainage with sterile packing dressing. In the other patient, the cause of repeated keloid inflammation was found to be an iatrogenic small peritoneal defect due to previous surgery. She was sent to general surgery part for additional diagnostic work-up and proper management. From these, we could infer the inflammation of umbilical keloid can be caused by a lot of reasons and require much attention for diagnosis. Thus, we will discuss appropriate diagnostic and therapeutic approach for secondary infection of umbilical keloid.

 

Sunmin Yim

Resident in Kangbuk Samsung Hospital, South Korea

Title: A Case of Inverted Type A (Clonal) Nevus
Biography:

Dr.Sunmin Yim  is resident in  Kangbuk Samsung  Hospital.

 

Abstract:

Inverted type A (clonal) nevus is a unusual type of melanocytic nevus. It contains pigmented nests of type A nevus cells in the depth of a banal. The nest is occasionally surrounded by type B or C nevus cells. Therefore, type A nevus cells are layered in deeper portion of nevus and Type B and C nevus cells are observed on superficial layers. An unusual presentation of inverted type A nevus have been rarely reported with superficial neurotization.

We described a case of a 68 year-old female complained of solitary, 0.4 cm-sized, dome shaped, brownish to skin-colored papule on the occiput. There was no pruritus or pain on the lesion. The excision biopsy was performed. The histology examination revealed clustered, swirling, epithelioid, type A nevus cells proliferation in the deep portion of perifollicular area. The dense, basophilic type B nevus cells were surrounding the nests of type A cells. Moreover, extensive neurotized type C nevus cells appeared in the upper dermis. No atypia and abnormal mitosis were observed. It could be diagnosed with inverted type A nevus based on the clinical and histological findings.

 

 

Jin-Chul Kim

Department of Medical Biomaterials Engineering, College of Biomedical Science and Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, Kangwon-do, Republic of Korea

Title: Possibility for use as a cosmeceutical material of reduction-responsive monoolein cubic phase containing epidermal growth factor
Biography:

Jin-Chul Kim is a full professor in the Kangwon national university (Department of Medical Biomaterials Engineering, College of Biomedical Science and Institute of Bioscience and Biotechnology), South Korea. One of his research interests is stimuli-responsive drug delivery system.

Abstract:

Monoolein can be eaten without causing an immune response to the human body and is used as an emulsifier in food and pharmaceutical fields. When monoolein is contacted with excess water, a cubic phase is spontaneously formed. Water channels with diameters of 2 nm to 10 nm cross each other and pass through the cubic phase, while the water channels are separated by a monoolein bilayer. These water channels encompass hydrophilic compounds and the monoolein bilayer can carry hydrophobic compounds. Cubic phase nanoparticles are small in size and have a high affinity for lipid filling between the cells of the skin, so they can penetrate through the intercellular pathways of the skin.

Reduction-responsive monoolein cubic phase was designed by immobilizing alginate and cystamine in the water channel of the cubic phase. The light scattering intensity of cystamine/alginate and alginate/EGF mixture solution were measured to investigate the crosslinking degree and the complex coacervation. Lipid bilayers and water channels, characteristic of cubic phase, were found on the TEM micrograph. According to the differential scanning calorimetric study, the phase transition occurred at 63.2℃ and it decreased significantly upon the inclusion of STAC and cystamine. Almost the same phase transition temperature was observed by polarized optical microscopy. The release degree of EGF loaded in the cubic phase increased as GSH concentration increased. It also increased with increasing pH value. Furthermore, the cubic phase did not show any skin irritation or mucosal irritation, in clinical tests.

 

Wen Hsien Ethan Huang

Aesthetic surgeon and Dermatologist, President of Taiwan International Academy of Anti- aging Educator’s Training

Title: Enhancing Your Rear is not Rare in China: Creating a Curvy Silhouette with New Needle-Hub Buttock Threading
Biography:

Dr. Wen Hsien Ethan Huang was born on Mar. 07, 1965, in Taiwan. He is a qualified aesthetic surgeon and dermatologist both in China and Taiwan. He is the advocater of needle-hub thread lift (NHTL) and inventor of ThreaFa Tight® Series and also co-inventor of GeneHope Facial Analyzer 2.0 plus. He started working in aesthetic medicine since 1999 and later joined GeneHope group in the year of 2011. He is now president of Taiwan International Academy of Anti- aging Educator’s Training, president of Threafa Tight ® Biotech Ltd. and CEO/CMTO at GeneHope Biotech Ltd. His work has centered around building a sustainable anti-aging path to the future, and in particular has unceasingly make effort to increase innovative patents in various territories and works steadily and makes solid progress to meet all the market requirements. He developed the innovative software-assisted NHTL technology which exhibits promising clinical results and offers a superior guideline for thread lifting. He is known for his prominent professional role both in China and Taiwan. His research interests include innovation of medical devices, aesthetic AVMR, Computer Vision (CV), Machine Learning (ML), Deep Learning (DL), aesthetic medical robotics.

Abstract:

The purpose of this study was to evaluate the results of gluteal suspension with new needle-hub buttock threading in China. Thirty healthy female patients in China between the ages of 40 and 60(mean, 45 years), who wished to remodel their buttocks from October 2015 to January 2018 were studied retrospectively. All 30 patients were treated with on each buttock using the following procedures: 12(40%) patients were suspended with new needle-hub threading alone; 18(60%) patients were more treated with microfocused ultrasound (Ultherapy) and radiofrequency (Thermage) in the lower back, supragluteal regions, and flanks to improve buttocks contour. Over a 2-year period, 30 female patients underwent gluteal suspension procedures. Good aesthetic results without complications were obtained in 27 of 30(90%) cases. Complication occurred in 3 of 30 (10%) patients, including thread removal due to postoperative pain in 1 (3%) patient, and thread protruding due to early heavy exercise in 2 (6%) patients. The results of this study performed in 30 patients over 2 years in China showed that the suspension with new needle-hub buttock threading performed as a single procedure or in combination with other cosmetic methods helps to enhance and lift ptosed gluteal and paragluteal areas and demonstrates an effective alternative to achieving improved lower gluteal fold contour with very good symmetry and patient satisfaction. The proper selection of patients and the procedures are paramount to achieving a successful outcome.

Biography:

Aishwarya Patil is interested in Dermatology as well as Cosmetology

Abstract:

 

Sjogren Larson syndrome is an inborn lipid metabolism error inherited in autosomal recessive pattern presenting as congenital ichthyosis, spastic diplegia/tetraplegia, and mental retardation caused by deficiency of enzyme fatty aldehyde dehydrogenase[FALDH]due to mutations in ALDH3A2 gene.

A 2yrs old male child presented with complaints of dry scaly and thickened skin ,with delayed development. On detailed history child attained neck holding at 7 months and sitting without support at 1and ½ yr with tightness and stiffness in lower limbs and episodes of seizures. No history of itching ,consanguinity of marriage and preterm birth. Cutaneous examination revealed dirty velvety plaques involving bilateral axillae, neck, groin and abdomen and plate like scales adherent at centre and free margins involving bilateral legs with generalised dryness over whole body.Neurological examination revealed global developmental delay with mental and growth retardation with increased ton in both lover limbs.Sjogren–Larsson syndrome is a rare syndrome which classically presents as developmental delay, mental retardation, speech difficulties, seizures, spastic diplegia/tetraplegia, Glistening white dots on retina, and skin involvement in the form of pruritus with ichthyosis with generalized hyperkeratosis. The case of Sjogren-Larsson syndrome for its rareity and classical clinical findings.

 

Kruti Banodkar

Consultant in K J Somaiya superspeciality Hospital

Title: MANAGEMENT OF SIDE EFFECTS OF INJECTABLES IN DERMATOLOGY
Biography:

Dr. Kruti Banodkar is a dermatologist practising since 9 years. She has completed her DNB in dermatology from KJ Somaiya Hospital & she is now a consultant in K J Somaiya superspeciality Hospital. She has won  a number of awards for presentations in national & international conferences. She also has articles published in dermatology journals. 
 

 

Abstract:

Commonly used injectables in dermatology include fillers, Botox, intralesional steroids, 5 fluorouracil, platelet rich plasma etc. They are generally considered safe. However side effects may happen and hence one needs to be aware of such side effects, contraindications & precautions to be adopted while using injectables.To make dermatologists aware about common side effects of  injectables & to arrive at a consensus in prevention and management of these side effects. Reports of different injectables’ complications in medical literature were reviewed & based on the publications retrieved and the authors’ extensive experience, recommendations for avoiding and managing complications are provided.

Different injectables have widely varying properties, associated risks & injection requirements. All injectables have the potential to cause complications. The majority of adverse reactions are mild and transient, such as bruising and trauma-related edema. Serious adverse events are rare & most are avoidable with proper planning & technique.Many strategies exist to reduce the risks of complications of injectables. A good working knowledge of side effects profiles of each product is mandatory. Although unwanted reactions are rare when proper planning and injection technique is used, dermatologists should be aware that unforeseen adverse sequelae can always occur. For optimum outcomes, one should have a detailed understanding of anatomy of the area, individual characteristics of products; their indications, contraindications, benefits, drawbacks; and ways to prevent potential complications. This spread of information is the need of the hour with the number of injectables increasing multifold in practice.

 

 

Neti sai Prasanth

PRATHIMA INSTITUTE OF MEDICAL SCIENCES ,KARIMNAGAR ,INDIA

Title: SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS WITH SCABIES
Biography:

Neti sai Prasanth  is currently working in Prathima Institute of Medical sciences, India

Abstract:

Subacute cutaneous lupus erythematosus is a clinically distinct subset of cases  of lupus erythematosus  which  usually  occurs  in young and middle aged women .It is characterized by papulosquamous and or polycyclic lesions in photodistributed  pattern .A 35year old female presented to OP with multiple palpulosquamous lesions on frontal and dorsalthorax  and  abdomen and on lateral  side of both upperlimbs  and in posterior auricular area.She had exfoliation of skin and intense itching all over the body. She also had crusted horny plaques on scalp, dorsal and frontal trunk and in posterior auricular area. The clinicalpresentation and laboratory studies were consistent with diagnosis of subacute cutaneous lupuserythematosus with Scabies. Topical permethrin for two weeks was given along with oralIvermectin 12mg stat . Horny localized plaques with crusting subsided in 2weeks.For Subacute lupus erythematosus she is given HCQS 200 mg.