Day 2 :
Keynote Forum
Moudad Alamatori
Chief of Derma/Venerology Dept and Ministry of health Swedaa Department
Keynote: Cutaneous tuberculosis study case
Biography:
Dr Moudad Alamatori Damascus University is specialized in Dermatology and Venerology. He is the chief of Derma/Venerology Dept and Ministry of health Swedaa Department , Swaidaa , Syria, chief of AIDS program He is having own Private Specific clinic, Swedaa, Syria.
Abstract:
M.H 15 year old Female Sweda Syria
The complain began seven years ago with chronic ulcers with facial erythma and upper lip enlargement.A well demarcated, slightly elevated infiltrated plaque with scarring in the center. The case has increased until total tissues loss [Pick Nose]Oral, Nasal mucosae are involved small, soft gray, ulcers, pink papules bleed easily.Pressure with a glass slide shows small yellowish-brown spots. Apple-jelly.Enlargement region lymph nodes.The diagnosed was cutaneous Leishmaniasis positive test.The patient had been treated with glucantim for one year no improvement has been occurred. The patient had been treated with anti-tuberculosis drugs with good results. Plastic surgery has been made after one year with good result.
- Aesthetic Surgical Procedures | Microdermabrasion | Pigmentation | Contagious Skin Infections
Chair
Andrea Merino-Ruisanchez
Universidad Popular Autonoma del Estado de Puebla (UPAEP), Puebla, Mexico
Co-Chair
Roberto Dell Avanzato
MD Medical Department of Espace Chenot Health Wellness & Spa, Italy
Session Introduction
Younghee Kim
Assistant Professor of the Department of Skin & Health Care at Suseong University
Title: E-BABE- Effect of anti-wrinkle cream on facial wrinkles
Biography:
Younghee Kim is an Assistant Professor of the Department of Skin & Health Care at Suseong University. She received her Ph.D. in Public Health from Keimyung University in 2009.
Abstract:
Skin wrinkles are induced by a marked loss of fibrillin-positive structures as well as a reduced content of collagen type VII, which contribute to weakening the bond between dermis and epidermis of extrinsically age skin. To prevent or improve the skin wrinkles, various strategies, including anti-wrinkle creams, have been pertained to the primary structural components of the dermis, collagen, elastin and GAGs. The aim of study was to evaluate the relationship between long-term application of anti-wrinkle creams and the improvement of facial wrinkle score in participants with various demographic characteristics.This study included five participants with age range of 34-62 years. Information on age and occupation as well as skin condition and types of skin was collected. Arbitrary facial wrinkle score (0 (none) to 10 (maximum)) were examined at baseline and 8 weeks of anti-wrinkle creams treatment. The 8 weeks of treatment showed significantly decreased the degree of wrinkle around the eyes, with mean values (arbitrary unit) of 5.27 unit at baseline and 1.87 unit at 8 weeks of treatment. Similarly, in wrinkle around the mouth, the treatment of anti-wrinkle creams decreased the wrinkle, with mean values of 6.84 unit at baseline and 3.60 unit at 8 weeks of treatment. The results of this study suggest that long-term treatment of anti-wrinkle creams decreases the facial wrinkle in women having various demographic characteristics. Therefore, anti-wrinkle cosmetics is a useful preventive strategy in wrinkle formation in terms of the rejuvenation of the skin primary structural constituents and reduction of inflammatory reaction.
Vaishnavi Gowda
Amrita Institute Of Medical Sciences
Title: Atypical mycobacterial cutaneous infections: A 5 years retrospective study
Biography:
Vaishnavi Gowda is currently working in Amrita Institute Of Medical Sciences.
Abstract:
Atypical mycobacteria comprise a heterogeneous non-tuberculous group of acid-fast bacteria involving the skin. The aim of our study was to describe the clinical and pathological features and species profile of atypical mycobacteria with a special mention to treatment response. A retrospective-record based study of patients attending our hospital over the past 5-years was carried out. Of the 3,45,456 patients 33 cases (19 male, 14 female) of atypical mycobacterial cutaneous infections were diagnosed. Patients’ age ranged from 21-75 years and average duration of lesions was 15 months. The diagnosis was proved by direct smear (6.5%), skin biopsy (20.9%), tissue culture (47.8%) and polymerase chain reaction (24.8%). Gene xpert was also carried out in a few cases. All biopsies revealed granulomatous inflammation. The most common organism isolated was Mycobacterium marinum(84.8%) ,with the upper limb being the commonest site. Other species isolated included Mycobacterium fortuitum(10.9%) and Mycobacterium kansasii(4.3%). 32 patients received treatment and 31 responded. 26 patients were treated with oral tetracyclines. Duration of treatment ranged from 8 to 54 weeks. Cutaneous atypical mycobacterial infections are showing a rising trend with Mycobacterium marinum showing highest prevalence. Newer technologies like polymerase chain reaction and gene xpert provide a rapid and sensitive method to improve the diagnosis. Tetracycline group of antibiotics, especially minocycline is effective in cases caused by Mycobacterium marinum. Combination chemotherapy may be a better choice for infections caused by other species.
Yan Li
Physician of Department of Dermatology in Beijing Friendship Hospital
Title: Efficacy and Safety of Halometasone Cream to Treat Chronic Generalized Eczema and the Effects of Halometasone Cream on Serum Cortisol Levels
Biography:
Dr. Yan Li is attending physician of Department of Dermatology in Beijing Friendship Hospital, Capital Medical University. Research focus in dermatology and contact allergy, cosmetology laser, immunological dermatology. She was the member of Medical cosmetology of China Society of Integrated Traditional Chinese and Western Medicine. Contributing Editor of China Clinical physicians of Chinese Medicine Association. She was graduated from Peking university health science center and received Doctor of Medicine in 2009. She has published more than 30 papers in reputed journals
Abstract:
The aim of the study was to investigate the efficacy and safety of halometasone cream to treat chronic generalized eczema and the effects of halometasone cream on serum cortisol (COR) levels. Sixty consecutive outpatients diagnosed with chronic generalized eczema between January and April 2017 were included and divided into groups A, B, and C with a lesion area of 30%-40%, 41%-50%, and 51%-60%, respectively. Groups A, B, and C were treated with halometasone cream with a daily dose of 15 g, 20 g, and 30 g for 7-14 days, respectively. Ten patients were randomly selected from each group for serum COR measurement at days 0, 7, and 14. On day 14, group B had significantly higher cure rate (47.1%) than groups A (17.9%) and C (13.3%) and significantly higher effectiveness rate (82.4%) than group C (40.0%) (all P < 0.05). Serum COR levels were not affected in group A but were reduced significantly in groups B and C on days 7 and 14 (all P < 0.05). No adverse reaction was observed. Halometasone cream appeared to relieve chronic generalized eczema effectively and safely. High dosage (≥20 g daily for 14 days) may temporarily reduce endogenous COR production substantially, although it may be more effective.
WeiXu
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University
Title: Efficacy and safety of compound glycyrrhizin capsules in patients with chronic eczema: A multi-center, randomized, double-blind, placebo-controlled study
Biography:
Dr. WeiXu is Vice physician of Department of Dermatology in Beijing Friendship Hospital. Research focus in dermatology and contact allergy. She was the Youth deputy of Standing Committee of Dermotology Branch of Chinese Medicine Association. Contributing Editor of China Clinical physicians of Chinese Medicine Association, Specialist of the qualification of foreign physician who want to practice at Beijing. She was graduated from Capital Medical University and received Bachelor of Medicine degree in 1991. Graduated from Capital Medical University and received Master of Medicine, Major in Dermatology in 2004. She got a training of cosmetology laser medcine in 1997 at HongKong. From 2005 to 2006,she went to University of North Carolina at Chapel Hill, UNC ,USA as a visiting scholar for 1 year.
Abstract:
This multi-center, 1: 1randomized, double-blind, placebo-controlled study aimed to evaluate the efficacy and safety of the traditional Chinese medicine oral compound glycyrrhizin (OCG) for adult chronic eczema. Methods: A total of 199 patients were equally randomized to the treated group receiving OCG capsules 3 times daily 75mg/time and mometasone furoate 0.1% ointment once daily for 28 days and the placebo group receiving placebo and the topical cream. The eczema area and severity index (EASI) score, the Investigator’s Global Assessment (IGA) score, and visual analogue scale score of itching were evaluated. Results: On day 28 of the treatment, compared with the placebo group, the treated group showed significantly greater extent of reductions in the absolute EASI (-7.39±1.71 vs. -6.64±1.75, P=0.003) and IGA (-2.63 ± 0.75 vs. -2.34±0.70, P<0.05) from the corresponding baselines and had significantly higher proportions of patients achieving EASI 50 (96.8% vs. 87.9%, P=0.021) and EASI 75 (47.9% vs. 21.2%, P<0.001), patients achieving IGA scores of clear (0) or almost clear (1) on day 28 (93.5% vs. 79.4%, P=0.005), and patients showing pruritus attenuation ( 94.7% vs. 83.8%, P=0.016). The treated group showed significantly less recurrence than the placebo group (3.19% vs. 12.12%, P=0.021). Adverse events occurred in 11 patients including 3 in the placebo group (3.0%) and 8 in the treated group (8.5%, P>0.05). Conclusion: OCG capsules combined with topical cream mometasone furoate 0.1% ointment is an effective and safe therapy for adult chronic eczema. Compound glycyrrhizin could be a promising steroid sparing agent for clinical application.
Biography:
WooKoung Lee is currently working in Root Hair Transplantation Center.
Abstract:
Follicular unit extraction has many advantages which is minimal scar, quicker recovery time but definitely have disadvantages as well. One of them include potential for high hair follicle transection rate. The disadvantage is mostly due to blind harvesting technique. Thus we had been looking for imaging methods which make visible technique possible. One of themis the ultrasound scanner which is 22MHz in frequency and shows structures within the dermis. Through it we found out that there were angle differences between hair shaft out of the skin and hair follicle in the occipital scalp. The results were in 20.8-40.3 degree range and 12.8 degree of average. In addition there were significance differences in the average follicle angle depending on the area of occipital region. Therefore we employed it’s data in order to reduce transection rate for graft. But despite ultrasound’s great ability, we was not able to harvest the grafts simultaneously while seeing the hair follicle. So we were searching for something to be capable of resolving the problem and lights gave us good idea. We made the first attempt with the NIR(one kind of lights which is 700-2500nm in wavelength). We were able to identify the hair follicles, but felt a need for further improvement. The most suitable amount of melanin to be observed in hair follicles was 640 nm red visible. We were able to identify hair follicles using 640nm red visible light with PL filter. As a result, we can harvest the grafts while looking at the hair follicles through the monitor simultaneously. While harvesting the hair follicle, we always have potential for transection of it when just depend on blind technique. We have been making much effort to lower transection rate of the follicle and at last we found out Follicoscope and ultrasound scanner. They consequently make visible technique possible. Sincerely I hope that you will provide a chance to demonstrate these equipments to participants.
Renni Yuniati
Medical Trainee
Title: EXPERIENCE IN TREATING SUBCLINICAL LEPROSY PATIENTS IN INDONESIA
Biography:
Renni Yuniati is currently doing her research at Leprosy.
Abstract:
Leprosy remains an important health problem in a number of regions and still a public health problem in Indonesia because leprosy generally manifest as neurodegenerative disorder which may lead to permanen disability, morbidity, and social stigmata. Early detection of infection, followed by effective treatment, is critical to reduce disease progression. New sensitive and specific tools for early detection of infection will be a critical component of an effective leprosy elimination campaign. Diagnosis is made by recognizing clinical signs and symptoms, but few clinicians are able to confidently identify these. Simple tests to facilitate referral to leprosy experts are not widely available, and the correct diagnosis of leprosy is often delayed. Indonesia have many research about prevalence of subclinical leprosy in population who live with leprosy patients or contact person and hospital employee in order to determine the rate of transmission and initiate early treatment for those with subclinical disease as well as providing data for future research. The leprosy status of the sample was evaluated using IgM anti-PGL-1 in the serum.
Biography:
Abstract:
Trophic ulcers secondary to leprosy pose a great stigma to the patients and remain a challenge to the treating dermatologists. The discovery of Platelet Rich Fibrin clot (PRF) with its favourable role in wound healing is a boon for the patients. PRF introduces the growth factors directly into the wound and aids in rapid healing. There has been less study performed for its use in trophic ulcers in hansen’s disease so our study brings out the use PRF in treating non healing ulcers in hansens disease. 5 patients (50%) showed complete healing, in 4 patients (40%) there was marked reduction in wound size and 1 patient (10%) lost to follow up. Mean healing time of ulcer is 5 weeks. PRF therapy leads to faster rate of induction of granulation tissue with rapid healing. It is a simple, safe and cost effective opd procedure, albeit requiring an optimal set-up and expertise. More sample size will be required for definitive results.