Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 21st World Dermatology Congress Tokyo, Japan.

Day 1 :

  • Dermatology | Cosmetic Dermatology | Dermatopathology | Dermatological Diseases | Trichology and Hair Transplant

Session Introduction

Sapna Gohil

University Hospitals of Coventry and Warwickshire, United Kingdom

Title: Money matters: A review of cost effective biologic prescribing at a Large Acute University Hospital
Speaker
Biography:

Sapna Gohil graduated in 2008 achieving First class Honours in a Master of Pharmacy degree in Leicester, UK. She has since achieved Distinction in the Postgraduate Clinical Pharmacy Diploma and has trained to become an Independent Prescriber. At present, Sapna manages high cost medicines for a variety of specialist areas such as Dermatology, Gastroenterology and Rheumatology. Such diverse experiences have formed the foundations of Sapna's current role as Lead Pharmacist for High Cost Drugs and Homecare Services at UHCW, a dynamic role requiring effective liaison with a variety of stakeholders in the national/local management and commissioning of High Cost Drugs. 

Abstract:

The practice of non-medical switching between originator biologic medicines and biosimilars resonates with recommendations from Lord Carter’s 2016 UK report regarding adoption of cost saving opportunities. In 2018/19, UHCW actioned one of the largest non-medical biosimilar switches for adalimumab.

This quantitative review explores the success of the adalimumab biosimilar switch and key themes associated with switch backs/refusals across the Dermatology (D), Rheumatology (R) and Gastroenterology (G) specialities at UHCW.

403 patients eligible for switch (R;189, G;176, D; 38) were considered between April-December 2019. Patients were informed in advance via a patient information leaflet/hospital clinic visits. Switch refusals, withheld treatments and cancellations were documented. Clinicians would provide alternative management plans for patients who reported significant concerns post switch.

264/403 patients successfully switched (R;122, G;109, D;33). 33/403 patients switched back to the originator (R;22, G;10; D;1). Of the 33 switch back patients; 12(36%)=reported lack of efficacy; 8(24%)=injection site pain and 13(39%)=various other factors such as blepharitis, unstable disease and pregnancy.

38/403 patients refused the switch and remained on the originator biologic (R;11, G;27, D;0). 29/403 patients switched to an alternative biologic (R;17, G;9, D;3). 32/403 patients stopped treatment (R;13, G;19, D;0). Treatment was withheld for 7/403 patients (R;4, G;2, D;1).

In summary, 66% of all eligible patients switched; thus an annual cost saving of £73,020. Dermatology achieved the most success in switching 87% of their patients. Injection site pain and subjective lack of efficacy were the predominant causative themes for switch backs.

Speaker
Biography:

Harshita Jain has completed her MBBS at the age of 23 years from Peoples University and Ongoing Postdoctoral studies from Teerthankar Mahaveer University in batch of 2018, and complete Dermatology degree by 2021.

Abstract:

Determinants of Quality of life in Psoriasis patients : A study from tertiary care centre in western Uttar Pradesh. Psoriasis is an immune-mediated disease that causes raised, red, scaly patches to appear on the skin. Psoriasis typically affects the quality of life, increases the financial and psychological burden. Aim and objectives: To assess the clinical severity as well as quality of life in patients with Psoriasis. Material and methods: A total of 50 patient of psoriasis were included in the study, over a period of 6 months, attending the dermatology OPD of TMU, Moradabad. Strict inclusion and exclusion criteria was followed. We measured clinical severity using Dermatology life quality index and Psoriasis area severity index. Statistical analysis was performed using unpaired independent student’s t-test, analysis of variance and Pearson’s correlation coefficients. Results: Among the Fifty psoriasis patients, there was a significant correlation between the severity of psoriasis and the extent of impact of psoriasis on physical disability as measured by the PDI. We have identified that a early age at onset of disease and stress exacerbators suffers greater disability in most aspects of quality of life. Conclusion: On the basis of this study, we would recommend that the quality of life in psoriasis is affected by both the severity and financial status of the patients. We recommend that the psoriasis patient require treatment approach that involves both medical and psychological measures regarding the disease.

 

Speaker
Biography:

Donatella Paolino, PhD. PharmD., has completed his PhD in "Technologies of the Biologically Active Substances" in 2003 at the University of Palermo (IT). At today she is Full Professor of Nanomedicine at the University Magna Graecia of Catanzaro (IT). She has published more than 140 papers in peer reviewed journals. She is serving as an editorial board member of different peer reviewed journals and she is serving as Editor-in-Chief for the Section "Nanomedicine and Nanotechnology “ of Pharmaceutics and is a mean. 

Abstract:

Psoriasis is a chronic, multifactorial disorder, influenced by both genetic and environmental factors of the skin. It generally have a significant negative impact on the physical, emotional, and, psychosocial wellbeing of affected patients. It may presents several clinical cutaneous manifestations, but most commonly it presents plaques (that effects 80% of patients and that mostly conditionate at social level them).

Daphne laureola L., (Italian: dame laurella), is a species of Daphne, of the Thymelaeaceae family. Its aqueous extract showed interesting profile for the topical treatment of the psoriasis plaques. It demostrated an excellent activity both in vitro (reducing the hyperproliferation of human fibrobalsts in a suitable in vitro model) and in vivo on patients affected by psoriasis plaques. In particular a gel based on Dafne Laureola extract, was applied topically by 90, selected patients affected by moderate and severe psoriasis plaques. The gel, applied twice a day, led to the complete reduction of psoriasis plaques in an average period of 20 days. At the complete remission of the plaques, the treatment was applied one a day for a period of 30 days, the 95% of the treated patients didn’t develope plaques for a minimun period of two years.

The proposed treatment represents a suitable remedy to relieve the symptomatology of the psoriasis and in particular to reduce the presence of plaques, very often responsible of social and emotional negative impacts.

 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Speaker
Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

 

 

Abstract:

As of June 15th, 2020, COVID-19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2] has infected 3.67 lakh patients in India bringing the world total to 8.4 million.

SARS-CoV 2 is an enveloped virus composed of positive sense single-stranded RNA and belongs to the coronavirus family. The lungs being the primary site of infection, with patients presenting symptoms ranging from a mild flu-like symptoms to fulminant pneumonia and potentially lethal respiratory distress.

Interestingly, there have been many COVID-19 cases reported with cutaneous manifestations. The purpose of this article is to provide an overview of various cutaneous manifestation in patients with COVID-19.

Studies conducted worldwide categorize observed COVID-associated skin patterns under 5 main categories:

  • Acral erythema with vesicles or pustules; so-called "pseudo-chilblains" – "covid toes”
  • Vesicular (chicken pox-like) eruptions
  • Maculopapular eruptions in 47% cases – most common cutaneous finding in covid-19 infected individual.
  • Urticaria
  • Livedoid manifestations

The aim of the study was to collect data from one of the largest covid dedicated facilities of north india, where cutaneous manifestations were observed (if any) in covid-19 admitted cases. According to our study 3 out of 550 covid infected patients showed livedoid manifestations. Data was also collected from 140 pediatric group of patients infected with covid-19, where none showed any skin manifestation. This study is probably the foremost and largest collection of cases from one of the biggest covid- dedicated hospital from north India. 

Speaker
Biography:

The first definition and diagnostic criteria for sick house syndrome in Japan (Sasagawa 2001).

Current Positionsï¼›Honorary member of the Japan Dermatological Association , Honorary member of the Osaka Dermatology Association ,Board-certified specialist of the Japan Dermatological Association, Advisor to Japan Organization of Clinical Dermatologists Kinki Block ,Councilor of the Japanese Society of Clinical Ecology ,Advisor to the Japan Society of Indoor Environment and Health, Advisor to the Osaka Dermatologic Association.Member of The Japanese Society for Medical Mycology.

Abstract:

The relation between tinea pedis and the internal environment of footwear has not been scientifically proven.

The onset of TP is also likely to be more affected by the internal environment of the footwear enveloping the feet than the climate outside the footwear.However, this relationship has not been directly proven in any study, and data on this relationship are lacking.This study aimed to determine whether the internal environment of footwear affects the incidence of tinea pedis and tinea unguium.

This cross-sectional, observatory study involved 420 outpatients who were categorized into non-tinea, tinea pedis, or tinea unguium groups based on mycological analysis. External climatic conditions, and temperature, humidity, and dew points inside the patients’ footwear were recorded. Result;People wearing footwear in an environment characterized by high temperature, high humidity, high temperature / high humidity, and high dew point had a significantly higher incidence of tinea pedis. ã€€Although this study does not contribute directly to clinical practice, it may enable dermatologists to advise patients on how to wear and maintain footwear, rather than limiting consultations to simply prescribing topical and internal agents. Consequently, dermatologists may play an important role in TP treatment and prevention.

Speaker
Biography:

Gulcan Yuksekal has completed his MD at the age of 23 years from Hacettepe University School of medicine Ankara, Turkey.  She is currently a research assistant in the dermatology department of the medical faculty of the university of Sakarya.


 

Abstract:

Intestinal microbiome is a large collection of bacteria, viruses, fungi and protozoa in our gastrointestinal (GIS) tract. Microbiome analyzes were also used to reveal the pathogenesis of some dermatological diseases such as acne vulgaris, psoriasis and atopic dermatitis. In addition to the skin microbiome, gut microbiome has a role in the pathogenesis of dermatological diseases.
 
In this study, we aimed to determine the possible relationship between CSU disease and gut microbiome, to determine the pathogenesis of CSU and to help new diagnosis and treatment approaches.
 
 
20 patients with CSU and 10 age and sex matched healthy individuals were included in the
present study. Both groups had not used a drug (antibiotics, proton pump inhibitors, etc.) or a probiotic/prebiotic that could affect gut microbiota for at least 4 weeks. After nucleic acid isolation from faecal samples, bacterial 16S ribosomal RNA (rRNA) gene target sequencing was performed with the Illumina MiSeq system using universal bacterial 16S primers (V3-V4). Statistical analyzes (LefSe, alpha and beta diversity) were performed after bioinformatics. The default settings (p <0.05 and LDA score> 2) identified taxa that differed significantly between the groups.
 
According to the results of series analysis; Bacteroidetes in patients with CSU and Actinobacteria phylum in healthy volunteers were significantly higher and Firmucites/Bacteroidetes ratio was lower in CSU patients.
 
As a result, there is a relationship between CSU disease and gut dysbiosis. Dysbiosis can be considered as an important factor in the pathogenesis of CSU and prebiotic or probiotics may be tried in the treatment. 
 

Biography:

Denise Barcelos is a dermatologist graduated 25 years ago, laser specialist, member of the Brazilian Society of Dermatology, Brazilian Society of Dermatologic Surgery, and Brazilian Laser Society in Medicine and Surgery.

Author of the book “A look at beauty”.

Abstract:

Objective: To determine the effect of ablative fractional photothermolysi resistant melasma.

Methods: 64 patients ( Fitzpatrick skin type 1 to 5) with resistant melasma were select. One session, of  2940nm ablative fractional Co2 laser were performed, and follow up the one session a year to maintenance. No other treatment was performed in the previous or subsequent months. The energy used ranged was very low from  5 mJ with 5% total coverage. Responses were evaluated by the researcher and the patients.

Results: 58 patients completed the study, out due side effects. In the opinion of the examining physicians,  52 patients the improvement at one month ranged from and for patients from 90% to 100%. Six patients achieved improvement of  75%  90% one month after the session. For patients the improvement at one month ranged. Previous impressions were maintained after years, with a anual session protocol, for the examining physician and the patients.

Conclusions: Efficient protocol with fractionated laser and drug delivery to resistent melasma with long term follow-up.

Speaker
Biography:

Denise Barcelos is a dermatologist graduated 25 years ago, laser specialist, member of the Brazilian Society of Dermatology, Brazilian Society of Dermatologic Surgery, and

Brazilian Laser Society in Medicine and Surgery.

Author of the book “A look at beauty".

Abstract:

Objective: To determine the effect of ablative fractional photothermolys resistant melasma.

Methods: 64 patients ( Fitzpatrick skin type 1 to 5) with resistant melasma were select. One session, of  2940nm ablative fractional Co2 laser were performed, and follow up the one session a year to maintenance. No other treatment was performed in the previous or subsequent months. The energy used ranged was very low from  5 mJ with 5% total coverage. Responses were evaluated by the researcher and the patients.

Results: 58 patients completed the study, out due side effects. In the opinion of the examining physicians,  52 patients the improvement at one month ranged from and for patients from 90% to 100%.

Six patients achieved improvement of  75%  90% one month after the session. For patients the improvement at one month ranged. Previous impressions were maintained after years, with a anual session protocol, for the examining physician and the patients.

Conclusions: Efficient protocol with fractionated laser and drug delivery to resistent melasma with long term follow-up.

Speaker
Biography:

Director of Chula cadaver workshops for botulinum toxin and HA filler. Founder of the Chula Soft Cadaver Surgical Training Center. Former Director of the Chula Soft Cadaver Surgical Training Center , 2000 - 2019. Former head department of Anatomy, 2004 - 2012. Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial hospital.

Qualification

Medical doctor, Chulalonhkorn University, 1986

Family medicine, Medical Council, 1998

Master Science of Clinical Epidemiology, Chulalongkorn University 2002

 

Abstract:

Background

Cannula injections at the nasolabial fold may face a risk of periarterial placement of filler. Compressions to temporary obliterate the facial artery may minimize the chance of arterial injury similar to injection of vasoconstrictor drug. 

Methods          

This study monitored five manual compression techniques for obliteration of the facial artery at the nasolabial fold using ultrasonographic imaging in 46 volunteers.

Results            

The ipsilateral mandibular compression temporary obliterated the facial artery at the nasolabial fold in 78 percent. The bilateral mandibular blocking sealed the artery in 93 percent.  The ipsilateral modiolar compression resulted in occlusion of the artery in 27 percent.  The ipsilateral modiolar and paraalar compression blocking effectively occluded the facial artery in 65 percent. The bilateral modiolar blocking obstructed the artery in 37 percent. 

Conclusion     

The compression techniques that effectively occlude the facial artery at the nasolabial fold in more than fifty percent of the cases to enhance safety of filler injections are: the bilateral mandibular compression (93%), ipsilateral mandibular compression (78%), and ipsilateral modiolar compression with paraalar compression (65%), respectively. These results provide alternative additional methods for physician’s individual preference.

Rachna Singh

Dermanation Skin Clinic, India

Title: Air Pollution & Premature Aging
Speaker
Biography:

Dr. Rachna Singh has completed her MBBS and Masters in Dermatology from India and she did diploma in Botox and filler from London (UK). She is a Director of Dermanation.

Abstract:

Skin aging process is due to Extrinsic factor as well as Intrinsic factor. Most common cause of extrinsic factor is Sun. Recently Air pollution by traffic/factories/ is also responsible for premature aging. Therefore in prevention of premature aging Air pollution also considered.

Speaker
Biography:

Dr. Joshua A. Arcaira is the incoming deputy chief resident at Makati Medical Center, Department of Dermatology in the Philippines. He completed his bachelor’s degree in Human Biology at De La Salle University - Manila with an honorable mention and graduated among the top 25th percentile of his batch in medical training at De La Salle Health Sciences Institute College of Medicine. Currently, he is interested in pursuing the subspecialties of Dermatologic Surgery and Dermatopathology.

 

Abstract:

Pemphigus Foliaceus (PF) is an uncommon autoimmune blistering disease with male predominance in Japanese literature, and onset within the 4th – 6th decades of life. We report a case of an elderly Filipino woman who presented with a one-year history of crusted erosions on the face, trunk, and extremities. Most lesions began as erythematous patches and plaques that would progress into flaccid bullae and woud easily erode. She was only maintained on irbesartan, atorvastatin, and multivitamins daily. There was no known familial history of blistering diseases. Skin punch biopsy revealed a vacuolar interface dermatitis and direct immunofluorescence showed granular intercellular staining of IgG and C3, anti-nuclear antibody stanining of IgG, and granular vascular staining of fibrinogen, consistent with Pemphigus group. Anti-nuclear antibody level was negative and serum ELISA levels showed positivity to only Desmoglein 1, and negative for Desmoglein 3-thus, clinching the diagnosis of PF. She was started on oral prednisone therapy at 0.75mg/kg/day and azathioprine 50mg/day, along with ranitidine, loratadine, diphenhydramine, calcium + vitamin D3 supplements, and a topical compounding of clobetasol propionate cream, fusidic acid cream, and a bland emollient. Clinical improvement was observed at one month of treatment where most lesions became darkly erythematous to hyperpigmenting thin plaques and no recurrence of erosions. Prednisone dosage was then slowly tapered to 5mg/day of prednisone at 4 months of treatment. No untoward events developed during the course of therapy except for one episode of upper respiratory tract infection which resolved after one week of Cefixime. Only 100 cases of PF were reported in the Philippine Dermatological Society Health Information System from 2011 to 2018 with female to male ratio of 2:3. This report aims to elucidate the importance of prompt recognition and treatment of this condition to achieve good prognosis and low morbidity.

 

Speaker
Biography:

Dr. Bashir Ahmad Barakzaie is the Dermatology Consultant, Dermatology Department, Herat Regional Hospital, Herat City – Afghanistan. 
 

Abstract:

Background:
 
Phytophotodermatitis — Topical exposure to plant-derived substances may also cause a phototoxic reaction termed phytophotodermatitis. Phytophotodermatitis occurs most commonly after exposure to limes and other plants. Other citrus fruits contain furocoumarins and may infrequently cause a phytophotodermatitis. Although generalized phototoxic reactions secondary to the ingestion of plants are rare, we admitted 17 cases of severe cutaneous reaction following ingestion of certain plants as a vegetable.
 
Observation:
 
During April – June 2018, 17 patients 5 (29.4%) men and 12 (70.6%) female, admitted to the dermatology department of our hospital for severe reaction in sun-exposed areas following ingestion of a particular plants called Shorak in local language (Salsa Rigid)as eatable vegetable food. 6 (35.2%) of patients were from Herat Province and the rest 11(64.8%) from Badghis. Both Herat and Badghis patients were all from the districts and rural areas, all were illiterate with only one just traditional semi-literate. The age ranged 2-56 years with an average of 22 years. The hospital staying time was between 1 – 17 days with an average length of stay of 5.9 days. The face was involved in all patients (100%), hands, feet, and necks affected by 64.7%, 53%, and 5.3% respectively. Only 1 patient (5.8%) face was involved alone. No patient had lesion elsewhere in the body without face involvement. Although, no mortality case reported, severe morbidity and disfiguring requiring skin graft seen in 4 cases and fingers amputation observed in one patient.
 
Key Message:
 
Even though phytophotodermatitis in particularly severe form is rare in other countries, it is still highly prevalent in our community leading to life long, disfiguring and disabilities. Hence, Strong efforts by policy-makers are required to deal with this public health challenge. We have already launched a massive media campaign and the links are available at YouTube.
 

Speaker
Biography:

Dr. Heena Singdia is a renowed dermatologist, working at department of dermatology, SMS Medical College, Jaipur, India. Her main works consist of studying the basic functions of skin by measuring various biophysical parameters in various dermatological disorders. She has presented her work in various national and international conferences and has won various awards for the same. 

Abstract:

Introduction
Macular amyloidosis  represents a common variant of primary localized cutaneous amyloidosis (PLCA) which  was first described by Palitz and Peck in 1952. Clinically, it  presents as poorly delineated hyperpigmented patches of grayish-brown macules with a rippled pattern, associated with deposition of amyloid material CYTOKERATIN- 5 in the papillary dermis distributed predominantly over  the interscapular area and extremities (shins and forearms) . Etiopathogenic factors - race, female gender, genetic predisposition (OSMR and IL31RA mutations), sun exposure, atopy and friction have been implicated. 
 
Our aim was to find out the melanin content and melanin index in the lesions of Macular amyloidosis and to incure whether melanin an plays important role in pigmentation of macular amyloidosis.  46 patients of macular amyloidosis of age group 18-40 yrs. were selected including 30 females and 16 males , Mexameter MX18 was used to measure melanin content and melanin index in the lesions of Macular amyloidosis over upper back and non-affected similar areas. Data was collected, fed into excel sheets and results were inferred.
 
Melanin index was raised in all the patients of cutaneous amyloidosis as compared to non-affected region of upper back where the ‘p’ value came out to be significant i.e. <0.05 in both males and females.
 
This study is first of its kind to evaluate the cause of pigmentation in cutaneous amyloidosis, Recent studies in melanoma have shown that amyloid acts as a precursor and accelerates the process of melanogenesis. Similar phenomenon may also exist in primary cutaneous amyloidosis. We recommend the use of strong antimelanotic agents and lasers in the treatment of macular amyloidosis.
 

Speaker
Biography:

Dr. Puneet Bhargava is working as senior professor at department of dermatology, SMS Medical College, Jaipur, India. He has around 80 publications in international and national journals. He was a Gold Medalist and is presently Editor of Indian Journal of Sexually Transmitted Diseases. His key interest areas include- vitiligo, leprosy,cutaneous drug reactions, and study of basic physiological functions of skin.

Abstract:

Inguinal skin is prone to various infectious dermatological conditions like – erythrasma, intertrigo, hidradinitis suppurativa, folliculitis, dermatophytic infection  and various sexually transmitted diseases.
 
This study  attempts to compare the biophysical profile parameters of the genital skin taking skin of the upper back as control, so as to find out , if there is a difference in BPPs in inguinal skin and rest of the body and that how the change in the BPPs, bring about change in microbiome and make inguinal skin more prone to infections.
 
We did a hospital based comparative study conducted over 976 patients (600 males and 376 females) , Age distribution (18-65years), where BPP parameters- Hydration, skin pH, TEWL, and sebum content were measured over skin of upper back and right inguinal region and the results were summarized and presented as proportions (%). Chi-square test was used to compare abnormal findings . ‘P’ value ≤0.05 was taken as significant. Medcalc 16.4 version software was used for all statistical calculations.
Significant difference was noted in skin pH , TEWL  and skin hydration, p value came out to be <0.05 which was significant, whereas there was minimal difference in Sebum content in both the areas.
 
Raised skin pH disturbs organization of lipid bilayers (disturbed barrier), decreases lipid processing (impaired SC cohesion) and increases serine proteases activity (reduced AMP). Increased TEWL (defect in physical barrier) and decreased Hydration predispose the genital skin to infections. Use of pH buffered solutions (3-4), barrier repair creams containing ceramides, and barrier protective creams with dimethicone, protection from trauma and friction can help prevent these inguinal dermatosis.
 

Speaker
Biography:

Dr. Rovira-Suetomi received her college degree at Rutgers, The State University of New Jersey, USA. She then took up Medicine at Mindanao State University in the Philippines. She completed her residency training in Dermatology at St. Luke’s Medical Center in Quezon City, Philippines. She is a diplomate of the Philippine Dermatological Society.  She currently heads Suetomi MD Dermatology Clinic in Iligan City, Philippines. 

Abstract:

Rosai Dorfman Disease (RDD), also known as Sinus Histiocytosis with Massive Lymphadenopathy (SHML) is a rare entity, which presents as painless cervical lymphadenopathy. Rarely does RDD involve the skin only. When it does, the disease is referred to as cutaneous RDD. We present a case of cutaneous RDD, an uncommon disease, which can be difficult to diagnose clinically and histopathologically, and challenging to treat. 
 
A 67-year-old female presented with a 9-month history of asymptomatic reddish brown papules and plaques overlying a movable indurated subcutaneous nodule on the left inner thigh. No lymphadenopathies were present. Review of systems was negative.  Medical history was noncontributory. Wedge biopsy was done.  Histopathology revealed nodular and diffuse dermatitis. Lymphocytes and plasma cells were seen within the cytoplasm of several large histiocytes, consistent with emperipolesis.  Immunohistochemistry was positive for CD68 and S-100, and negative for CD1a. Further evaluation through neck, chest & mediastinum, and whole abdominal CT scans revealed no systemic involvement. A final diagnosis of cutaneous RDD was made. 
 
Although the skin is one of the most common extranodal sites for RDD, cutaneous  RDD without nodal involvement is rare, accounting for about 3% of reported cases.  The lesions are painless, and it is less likely to have systemic involvement and constitutional features compared to nodal RDD. Owing to its favorable outcome and spontaneous resolution, cutaneous RDD should not be confused with other benign or malignant lesions.  Hence, aggressive treatment such as excision should not be presented as first-line of treatment.  In our patient, the lesion has decreased in size to 40% in 2 years with no other associated signs and symptoms.   
 
The importance of thorough diagnosis, circumspect management, and adequate patient education should be emphasized.  
 

Speaker
Biography:

Dr. Marisabel Mourelle has a wide experience in fundamental and applied research (about 100 scientific papers in Peer-Reviewed, Q1 Journals and various chapters in books published). She has been extensively working for the Pharmaceutical Industry, in charge of R&D departments among Mexico, USA, UK, Spain, with a strong focus on Drug Discovery, Preclinical and Clinical Drug Development and Toxicology. She has been also Manager of Intellectual Property and assistance to Business Development in Licensing-in and Licensing out. At the present, she is the Technical Director and Head of R&D+i Department at Infinitec Activos. She is also IP and new brands manager, closely collaborating with Sales and Marketing Department.

Abstract:

Introduction: It is well known the need of a stable vitamin C to assure delivery of real ascorbic acid (AA) inside skin to play its physiological roles as antioxidant and as inducer of collagen synthesis.
 
Aim: To design a new delivery system for Vit C. 
 
Material and Methods: We have conjugated AA with gold sub-­â€microparticles and also GSH to compensate any H2O2 may be generated by ascorbic acid oxidation under physiological conditions. AA was bound to gold by the active part of the molecule that assures the antioxidant activity. Therefore, the oxidative transformation into dehydroascorbic acid is prohibited. GSH was bound to gold through its SH group. Thus, after Golden C internalization, vit C is released in the intracellular medium as the active form vitamin C. 
 
Results: The size of the particles was measured by DLS being 164+/-­â€ 24 nm considered fully safe. Chemical stability of Golden C was evaluated and demonstrated in powder form, in water, in glycerine and in O/W emulsions. Results showed 100% stability after 6 months at 40ºC while the stability of free AA lasted only 48 h in water and 2 weeks in O/W emulsion. Skin penetration of Golden C was studied in pig skin using Franz cells showing that after 20 h of application, 74% of the applied dose was as AA in the fluid while 26 % still remaining inside the skin. When the same dose of SAP or AG, applied onto skin, no any AA was detected neither in the effluent nor inside the skin. By using the DPPH test the free radical scavenging properties of 0.03% Golden C was twice that offered by 0.03% free AA. In HDF in culture, 0,0003% golden C reduced 53% UV induced lip peroxidation. To observe the same level of protection using free AA a 10 times higher dose (0.003%) was needed. Golden C induces 66% increase collagen1 RNA expression in HDF while no induction was detected with the same dose of AA. Significant stimulation of collagen synthesis was confirmed immunohistologically using specific antibody in HDF. AA, at the same dose level tested (0.003%), was not able to stimulate collagen synthesis in HDF. In vivo studies evaluated the efficacy of Golden C (0.5% in a emulsion) vs placebo. The in vivo study was performed with Biozoom technology to measure betacarotene level after 15 min exposure to an oxidative challenge induced by either ozone or UV. Product was applied before challenge and skin carotene level measured. Golden C application counteracted by 70% the beta-­â€carotene loss induced by ozone or 50% the loss induced by UV radiation. 
 
Conclusion: Golden C constitutes a stable and efficacious form to deliver real vitamin C to skin.
 

Speaker
Biography:

WANG Lan is a PhD student of Chinese Medcine, from School of Chinese Medicine, The Chinese University of Hong Kong. Her supervisors are Prof. Lin Zhixiu, Associate Director of School of Chinese Medicine and Prof. Che Yuen Wu, Director of Hong Kong Institute of Integrative Medicine.
 

Abstract:

Atopic dermatitis (AD) is a common skin disorder characterized as erythema, eruption, lichenification and pruritus. Up to date, 2-10% of adults and 15-30% of children are suffering from AD. In this study, we aimed to evaluate the anti-AD effects of a Chinese medicines fomula (SZF) and elucidate its underlying mechanisms using a in vivo model. AD-like skin lesions in female BALB/c mice were induced by 2,4-dinitrochlorobenzene (DNCB). SZF (3.15, 6.30 and 9.45 g/kg) and dexamethasone were daily administered by gavage for 15 days. The body weight, skin thickness, skin dermatitis severity and scratching behaviors were recorded throughout the study. Histological analysis, rt-PCR, western blot and ELISA analysis were used to illuminate the molecular targets associated with anti-AD effects of SZF. SZF could significantly alleviate AD-like skin lesions and decrease dorsal skin thickening in DNCB-treated mice. DNCB induced scratching behaviors obviously reduced in SZF-treated mice. Infiltration of mast cells and epidermal thickening in dorsal skin were also inhibited by SZF treatment. Additionally, levels of AD-specific markers as IgE, histamine, IL-4 and TSLP in serum obviously decreased in SZF-treated mice. SZF reduced both the production and mRNA expression of Th2 cytokines IL-4, IL-6, IL-13 and IL-31 levels but increased Th1 cytokine IFN-γ level in the skin. SZF also up-regulated the protein expression of filaggrin, involucrin, and loricrin in the skin of DNCB-treated mice. SZF might exert therapeutic effect on DNCB induced AD-like skin lesions in mice through regulation of the Th1/Th2 balance, inhibition of inflammation and improvement of skin barrier function.

Speaker
Biography:

Dr Ehsan Hamifard is a cosmetic dermatologist,
He is a member of IMA in Dubai, DASIL & WCOCD.
He is specialist in fat grafting for face & body.
 

Abstract:

Nanofat is emulsified (liquefied) and filtered fat. The fat cells have been crushed and filtered out and what remains is a liquid that contains a high concentration of stem cells.

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through cell division) to produce more stem cells. Stem cells are very important in the regeneration of damaged tissues.

Millifat is large parcel sized (2.4 mm and <) fat that is used when structural fat grafts are performed for deep fat compartment filling, filling of the lips, temporal regions, brows, chin, nose, and pyriform. 

From last year till now we have used both nonofat & millifat in face rejuvenation simultaneously in more than 500 cases & have achieved very wonderful results.

This method can be used instead of other methods of face rejuvenation & face filling due to less costs & natural components.

 

Speaker
Biography:

Vilashini. V has completed her undergraduate M.B.B.S., in PSG IMSR, Coimbatore and is currently pursuing first year  post graduation in M.D., Dermatology in Chettinad hospital and research institute, Kelambakkam , Tamilnadu, India. 

Abstract:

Introduction:  Pityriasis Rosea is a acute self-limiting papulosquamous dermatosis localized in trunk and extremities, seen more frequently in adolescents and young adults. Atypical variants are rare accounting to approximately 20 % of all cases. Atypical presentations in PR can lead to difficulty in diagnosis. Here I present a previously unreported rare atypical case of Bullous Pityriasis Rosea in a 7-year-old child. 
 
Materials and Method:
 
Case Report-
A 7-year-old male child presented with 3-4 cm in size erosions with overlying minute pustules and vesicles in the upper and lower extremities.  History of bullous lesions, which progressed to the current erosions present for the past seven days. History of similar lesions, which remitted and relapsed, on its own even without any treatment, since childhood, was told by the parent. Based on the clinical findings and presentations, differential diagnosis included chronic bullous impetigo, bullous mastocytosis, chronic bullous disorder of childhood. Skin biopsy was done.  Histopathology showed features consistent with Pityriasis Rosea.
 
Discussion: PR presenting in bullous form is by itself an atypical presentation. On top of that, the disease having a remitting and relapsing course is even more rare. Though PR is a common self-limiting disease, recognition of disease variants with respect to morphology, location and evolution of lesions may avoid unnecessary procedures and drug ingestion.
 

Speaker
Biography:

Dr. Pei Swam Ng, as a proud dean list graduate of Bachelor of medicine and Bachelor of Medicine (MBBS) from University of Malaya, Kuala Lumpur. She obtained the Medical Asethetic Certificate (MAC) and she was also trained locally and abroad. She is an expert in anti-aging solution and main area of interests are regenerative medicine (stem cell, PRP and bioidentical hormone therapy) and facial injectables.

Abstract:

Introduction
PRP is a cutting-edge form of regenerative medicine that has widely used for aesthetic medicine. Despite increasing in popularity, there is still lacking of evidence support due to the lack of consistent method in application.
 
Objective
To assess the clinical efficacy and patient satisfaction of a 3-months PRP treatment regime for facial rejuvenation in different age group patients.
 
Method
51 patients ranging from 20 to 59 years of age were recruited for this study. They were divided into two groups according to their age: Group A (20-39 years of age) included 20 patients and Group B (40-59 years of age) included 31 patients. Written consent was taken. All patients received total six sessions of PRP treatment at 2-week interval. Nine mililitre of PRP were injected into 8 standardized points. Assessment was carried out using Severity Rating Scale (WSRS) and Global Aesthetic Improvement Scale (GAIS). Patients were followed up for 6 months.
 
Result
15 of 20 patients from Group A while 20 of 31 patients from Group B showed significant improvement in both WSRS and GAIS assessment. Group A patients resulted higher satisfaction level in their appearance. Safety profile of PRP treatment was excellent with minimal downtime.
 
Conclusion
3-months PRP treatment regime is effective and safe for facial rejuvenation resulting high satisfaction level on both age group patients. This treatment regime could be considered as an effective procedure for skin maintenance.