19th World Dermatology Congress May 07-08, 2018 Tokyo, Japan

Biography:

Roberto Dell’Avanzato is the  Managing Director of Medical Department of Espace Chenot Health Wellness & Spa

Abstract:

A new procedure that represents the only FDA-cleared minimally invasive treatment clinically proven to improve the cellulite blemishes for nearly four years in only one session.The procedure treated successfully the primary structural cause of cellulite blemishes in all the 50 patients. Patient satisfaction was 87% at T90 in 50 patients 95% at T180 in 50 patients, 97% at 12 months in 13 patients and 100% at 15 months in 3 patients. Transient treatment-related adverse events were mild in severity and the most common side effects reported were soreness and bruising. Among 50 patients, 95% had bruising at T7, 23% at T14 and no patient had bruising at T30. Soreness is reported in 100% of patients at T7, 19% at T14, 4% at T30 and 0% at T90. Global Aesthetic Improvement Scale and Visual Analog Scale are also reported. This revolutionary FDA-cleared procedure for the cellulite puckering, combines a proven approach with an innovative technology to treat the primary structural cause of cellulite blemishes in posterior thighs and buttocks. This study confirms his safety, and efficacy with vacuum-assisted precise tissue release for the treatment of cellulite, which is also strengthened by patients satisfaction.

Biography:

Theodore D. Zaki, is the  Managing Director of Yale University School of Medicine, USA

Abstract:

The patient is a 75-year-old woman with seropositive RA with polyarthropathy, who had recently started adalimumab presented with a diffuse skin eruption. She had been previously treated with tocilizumab (4mg/kg monthly), methotrexate (10 mg weekly), and prednisone (5 mg weekly), with declining therapeutic effect. She was to undergo treatment with adalimumab (40 mg / 2 weeks). The patient reported that she administered a first adalimumab injection in the right lower abdominal quadrant two weeks prior to dermatologic evaluation. One day prior to dermatologic evaluation, she noted a round rash at the injection site and then overnight developed multiple skin lesions. She reported pruritus but otherwise felt well. Of note, she had taken 2 g of amoxicillin four days prior for a dental procedure. She had no additional medications. Physical examination revealed an 8 cm round erythematous patch with central, dusky hyperpigmentation over the right abdomen. There were numerous 3-8 mm urticarial macules and papules scattered over the legs, trunk, and arms, some with dusky centers. Urticarial patches were present on the palms. Oral mucosa and conjunctivae were unremarkable.A punch biopsy of the abdominal injection site showed perivascular lymphocytes and eosinophils, indicative of a drug eruption. Punch biopsy of an urticarial papule on the left thigh showed LCV, characterized by fibrinoid degeneration of small blood vessels and a mixed infiltrate, with abundant neutrophils and prominent nuclear dust. Various adverse events have been reported in clinical trials of subcutaneous TNF-α inhibitors, most commonly ISRs. ISR, by definition, includes any of: erythema, pruritus, hemorrhage, pain, or swelling at the site of injection. LCV is a small vessel vasculitis involving dermal postcapillary venules. Drugs cause roughly 10% of LCV, which generally manifest between 7 and 21 days following treatment. Numerous studies have associated anti-TNF-α therapy with vasculitis,7-10 most commonly cutaneous vasculitis (most prevalent in patients with RA).8 During RA clinical trials using adalimumab, the incidence of LCV was 0.01 events per 100 person-years of exposure.4 The pathogenesis of anti-TNF-α associated vasculitis remains unclear. One hypothesis is that anti-drug host antibodies initiate an immune-complex mediated hypersensitivity reaction. Another theory suggests that TNF-α antagonists induce a switch from the predominant T helper 1 (Th1) profile of RA to a Th2 response.The skin lesions began at the injection site and subsequently spread. Given the injection site localization and the time course, adalimumab was presumed to be causative. It is possible that amoxicillin could also have caused the diffuse eruption. Our patient was successfully treated with discontinuation of adalimumab and initiation of corticosteroid therapy, with antihistamines as needed.

Biography:

Lilia Rabenok is working in Medicina Cirugia Estetica Ambulatoria in Mexico.

Abstract:

 One patient with Gynecomasty was examined and using surgical treatment in combinating with liposuccion  of  breath and  body in out-patient clinic.  After the surgical treatmen we used a radiofrecuency field twice a week during 4 weeks. Good results of medical treatment without complications were observed in this case. We conclude that using surgical treatment and radiofrecuency field after the surgery is effective in complex treatment of gynecomasty in out-patient clinic.

Biography:

Dr Moudad Alamatori  Damascus University is specialized in  Dermatology and Venerology. He is having experience in Swaidaa government hospital , Swaidaa, Syria. He is the Ministry of health Swedaa Department , Swaidaa , Syria and chief of AIDS program. He is having own Private Specific clinic, Swedaa, Syria.

Abstract:

M.H 15 year old Female Sweda Syria and the complain began seven years ago with chronic ulcers with facial erythma and upper lip enlargement.A well demarcated, slightly elevated infiltrated plaque with scarring in the centerThe case has increased until total tissues loss [Pick Nose]Oral, Nasal mucosae are involved small, soft gray, ulcers, pink papules bleed easily.Pressure with a glass slide shows small yellowish-brown spots. Apple-jelly.Enlargement region lymph nodes.The diagnosed was cutaneous Leishmaniasis positive test.The patient had been treated with glucantim for one year no improvement has been occurred.Plastic surgery has been made after one year with good result.

Biography:

Dr.Yun Ho Lee is resident in  Kangbuk Samsung  Hospital

Abstract:

27 patients (13 males and 14 females, mean age 46.7 ± 15.7 years) were analyzed. A total of 151 nails, consisting of 105 finger nails and 46 toe nails, were treated with a 1064 nm PSNY. The mean treatment session was 7.5 ± 4.2. After receiving a 1064nm PSNY laser therapy, 16 patients (59 %) showed more than 50 % improvement. There were no serious adverse events associated with the treatment during follow-up period. Idiopathic onychodystrophy successfully treated with a 1064nm PSNY laser. This device offers a new and potentially therapeutic modality for the patients with idiopathic onychodystrophy.

Biography:

Dr.Jae Yun Lim  is  resident in  Kangbuk Samsung Hospital.

Abstract:

Skin squamous cell carcinoma (SCC) presents as papules or plaques with erythematous or pigmented appearance that may ulcerate the skin. There are few reports from literature that SCC presents as skin cellulitis. By knowing the unusual presentations of SCC and diagnosing SCC in the early stage, advanced metastasis of the disease can be prevented and good prognosis with modest mean survival rate can be achieved.A 73-year-old female presented with diffuse erythematous patches with heating sense on left thigh. The patient received wide excision of well-differentiated squamous cell carcinoma of left shin 4 years ago. The patient was treated as an outpatient for cellulitis with antibiotics, which produced almost complete improvement after 6 months. However, multiple tiny erythematous papules with diffuse erythematous patches on left thigh were persistent after 6 months of antibiotics treatment. Punch biopsy of the lesion confirmed well-differentiated, microinvasive squamous cell carcinoma. The histologic examination of the lesion showed scattered atypical squamoid and basaloid tumor nests in the upper and deep dermal layer. Herein, we report a case with squamous cell carcinoma presenting as cellulitis.

Biography:

Dr. Junghwa Yang  is resident in  Kangbuk Samsung  Hospital.

Abstract:

White piedra is a superficial mycotic infection of the hair shaft, characterized by small, firm, irregular gritty nodules. This asymptomatic infection, also known as tinea nodosa and trichomycosis nodularis, is mainly caused by basidiomycetous yeasts in the genus Trichosporon. But rarely has this disease due to other fungi infection been reported and no case of white piedra in Korean was documented so far.

A 22-year-old man presented with palpable translucent to white nodules along the left temporal scalp hair. He denied other symptoms like scalp irritation or pruritus, but complained the affected hairs became brittle and easily broke at points of attached nodules. On the contrary, the adjacent scalp skin was not affected.

For the diagnosis, fungus culture from the affected hair on Sabouraud agar was performed and it revealed distinctive orange to red colonies, which were diagnostic of Rhodotorulla species. The patient was treated with oral itraconazole and isoconazole cream, and his symptom was clinically improved after a month with significant decrement of the concretions and brittle hairs.Thus, we will introduce this patient as a rare case of white piedra caused by Rhodotorula species.

Biography:

Dr. Hyeon Jeong Park   is resident in  Kangbuk Samsung  Hospital.

Abstract:

As many surgical operations have been replaced by laparoscopic surgery, the number of umbilical keloid patients is gradually increasing. Generally, as keloids are painful in the disease itself, clinical differentiation with secondary infection could be difficult. If a thick keloid is formed, it may be a hard problem to confirm the fluctuation and heat sensation in the physical examination. For these reasons, rapid and appropriate surgical intervention can be delayed in numerous umbilical keloid patients.

We experienced three cases of secondary keloid infection in our hospital. In two middle-aged women with tenderness of the keloid, an inflammatory epidermoid cyst was identified by incisional biopsy. Pus from the both patients was sent for microbiological examination, but any significant bacteria growth that might be a pathogenicity factor was not found. Both patients were treated by empirical antibiotics and pus drainage with sterile packing dressing. In the other patient, the cause of repeated keloid inflammation was found to be an iatrogenic small peritoneal defect due to previous surgery. She was sent to general surgery part for additional diagnostic work-up and proper management. From these, we could infer the inflammation of umbilical keloid can be caused by a lot of reasons and require much attention for diagnosis. Thus, we will discuss appropriate diagnostic and therapeutic approach for secondary infection of umbilical keloid.

Biography:

Dr.Sunmin Yim  is resident in  Kangbuk Samsung  Hospital.

Abstract:

Inverted type A (clonal) nevus is a unusual type of melanocytic nevus. It contains pigmented nests of type A nevus cells in the depth of a banal. The nest is occasionally surrounded by type B or C nevus cells. Therefore, type A nevus cells are layered in deeper portion of nevus and Type B and C nevus cells are observed on superficial layers. An unusual presentation of inverted type A nevus have been rarely reported with superficial neurotization.

We described a case of a 68 year-old female complained of solitary, 0.4 cm-sized, dome shaped, brownish to skin-colored papule on the occiput. There was no pruritus or pain on the lesion. The excision biopsy was performed. The histology examination revealed clustered, swirling, epithelioid, type A nevus cells proliferation in the deep portion of perifollicular area. The dense, basophilic type B nevus cells were surrounding the nests of type A cells. Moreover, extensive neurotized type C nevus cells appeared in the upper dermis. No atypia and abnormal mitosis were observed. It could be diagnosed with inverted type A nevus based on the clinical and histological findings.

Biography:

Jin-Chul Kim is a full professor in the Kangwon national university (Department of Medical Biomaterials Engineering, College of Biomedical Science and Institute of Bioscience and Biotechnology), South Korea. One of his research interests is stimuli-responsive drug delivery system.

Abstract:

Monoolein can be eaten without causing an immune response to the human body and is used as an emulsifier in food and pharmaceutical fields. When monoolein is contacted with excess water, a cubic phase is spontaneously formed. Water channels with diameters of 2 nm to 10 nm cross each other and pass through the cubic phase, while the water channels are separated by a monoolein bilayer. These water channels encompass hydrophilic compounds and the monoolein bilayer can carry hydrophobic compounds. Cubic phase nanoparticles are small in size and have a high affinity for lipid filling between the cells of the skin, so they can penetrate through the intercellular pathways of the skin.

Reduction-responsive monoolein cubic phase was designed by immobilizing alginate and cystamine in the water channel of the cubic phase. The light scattering intensity of cystamine/alginate and alginate/EGF mixture solution were measured to investigate the crosslinking degree and the complex coacervation. Lipid bilayers and water channels, characteristic of cubic phase, were found on the TEM micrograph. According to the differential scanning calorimetric study, the phase transition occurred at 63.2℃ and it decreased significantly upon the inclusion of STAC and cystamine. Almost the same phase transition temperature was observed by polarized optical microscopy. The release degree of EGF loaded in the cubic phase increased as GSH concentration increased. It also increased with increasing pH value. Furthermore, the cubic phase did not show any skin irritation or mucosal irritation, in clinical tests.

Biography:

Dr. Wen Hsien Ethan Huang was born on Mar. 07, 1965, in Taiwan. He is a qualified aesthetic surgeon and dermatologist both in China and Taiwan. He is the advocater of needle-hub thread lift (NHTL) and inventor of ThreaFa Tight® Series and also co-inventor of GeneHope Facial Analyzer 2.0 plus. He started working in aesthetic medicine since 1999 and later joined GeneHope group in the year of 2011. He is now president of Taiwan International Academy of Anti- aging Educator’s Training, president of Threafa Tight ® Biotech Ltd. and CEO/CMTO at GeneHope Biotech Ltd. His work has centered around building a sustainable anti-aging path to the future, and in particular has unceasingly make effort to increase innovative patents in various territories and works steadily and makes solid progress to meet all the market requirements. He developed the innovative software-assisted NHTL technology which exhibits promising clinical results and offers a superior guideline for thread lifting. He is known for his prominent professional role both in China and Taiwan. His research interests include innovation of medical devices, aesthetic AVMR, Computer Vision (CV), Machine Learning (ML), Deep Learning (DL), aesthetic medical robotics.

Abstract:

The purpose of this study was to evaluate the results of gluteal suspension with new needle-hub buttock threading in China. Thirty healthy female patients in China between the ages of 40 and 60(mean, 45 years), who wished to remodel their buttocks from October 2015 to January 2018 were studied retrospectively. All 30 patients were treated with on each buttock using the following procedures: 12(40%) patients were suspended with new needle-hub threading alone; 18(60%) patients were more treated with microfocused ultrasound (Ultherapy) and radiofrequency (Thermage) in the lower back, supragluteal regions, and flanks to improve buttocks contour. Over a 2-year period, 30 female patients underwent gluteal suspension procedures. Good aesthetic results without complications were obtained in 27 of 30(90%) cases. Complication occurred in 3 of 30 (10%) patients, including thread removal due to postoperative pain in 1 (3%) patient, and thread protruding due to early heavy exercise in 2 (6%) patients. The results of this study performed in 30 patients over 2 years in China showed that the suspension with new needle-hub buttock threading performed as a single procedure or in combination with other cosmetic methods helps to enhance and lift ptosed gluteal and paragluteal areas and demonstrates an effective alternative to achieving improved lower gluteal fold contour with very good symmetry and patient satisfaction. The proper selection of patients and the procedures are paramount to achieving a successful outcome.

Biography:

Aishwarya Patil is interested in Dermatology as well as Cosmetology

Abstract:

Sjogren Larson syndrome is an inborn lipid metabolism error inherited in autosomal recessive pattern presenting as congenital ichthyosis, spastic diplegia/tetraplegia, and mental retardation caused by deficiency of enzyme fatty aldehyde dehydrogenase[FALDH]due to mutations in ALDH3A2 gene.

A 2yrs old male child presented with complaints of dry scaly and thickened skin ,with delayed development. On detailed history child attained neck holding at 7 months and sitting without support at 1and ½ yr with tightness and stiffness in lower limbs and episodes of seizures. No history of itching ,consanguinity of marriage and preterm birth. Cutaneous examination revealed dirty velvety plaques involving bilateral axillae, neck, groin and abdomen and plate like scales adherent at centre and free margins involving bilateral legs with generalised dryness over whole body.Neurological examination revealed global developmental delay with mental and growth retardation with increased ton in both lover limbs.Sjogren–Larsson syndrome is a rare syndrome which classically presents as developmental delay, mental retardation, speech difficulties, seizures, spastic diplegia/tetraplegia, Glistening white dots on retina, and skin involvement in the form of pruritus with ichthyosis with generalized hyperkeratosis. The case of Sjogren-Larsson syndrome for its rareity and classical clinical findings.

Biography:

Dr. Kruti Banodkar is a dermatologist practising since 9 years. She has completed her DNB in dermatology from KJ Somaiya Hospital & she is now a consultant in K J Somaiya superspeciality Hospital. She has won  a number of awards for presentations in national & international conferences. She also has articles published in dermatology journals. 
 

Abstract:

Commonly used injectables in dermatology include fillers, Botox, intralesional steroids, 5 fluorouracil, platelet rich plasma etc. They are generally considered safe. However side effects may happen and hence one needs to be aware of such side effects, contraindications & precautions to be adopted while using injectables.To make dermatologists aware about common side effects of  injectables & to arrive at a consensus in prevention and management of these side effects. Reports of different injectables’ complications in medical literature were reviewed & based on the publications retrieved and the authors’ extensive experience, recommendations for avoiding and managing complications are provided.

Different injectables have widely varying properties, associated risks & injection requirements. All injectables have the potential to cause complications. The majority of adverse reactions are mild and transient, such as bruising and trauma-related edema. Serious adverse events are rare & most are avoidable with proper planning & technique.Many strategies exist to reduce the risks of complications of injectables. A good working knowledge of side effects profiles of each product is mandatory. Although unwanted reactions are rare when proper planning and injection technique is used, dermatologists should be aware that unforeseen adverse sequelae can always occur. For optimum outcomes, one should have a detailed understanding of anatomy of the area, individual characteristics of products; their indications, contraindications, benefits, drawbacks; and ways to prevent potential complications. This spread of information is the need of the hour with the number of injectables increasing multifold in practice.

Biography:

Neti sai Prasanth  is currently working in Prathima Institute of Medical sciences, India

Abstract:

Subacute cutaneous lupus erythematosus is a clinically distinct subset of cases  of lupus erythematosus  which  usually  occurs  in young and middle aged women .It is characterized by papulosquamous and or polycyclic lesions in photodistributed  pattern .A 35year old female presented to OP with multiple palpulosquamous lesions on frontal and dorsalthorax  and  abdomen and on lateral  side of both upperlimbs  and in posterior auricular area.She had exfoliation of skin and intense itching all over the body. She also had crusted horny plaques on scalp, dorsal and frontal trunk and in posterior auricular area. The clinicalpresentation and laboratory studies were consistent with diagnosis of subacute cutaneous lupuserythematosus with Scabies. Topical permethrin for two weeks was given along with oralIvermectin 12mg stat . Horny localized plaques with crusting subsided in 2weeks.For Subacute lupus erythematosus she is given HCQS 200 mg.

Biography:

Younghee Kim is an Assistant Professor of the Department of Skin & Health Care at Suseong University. She received her Ph.D. in Public Health from Keimyung University in 2009.

Abstract:

Skin wrinkles are induced by a marked loss of fibrillin-positive structures as well as a reduced content of collagen type VII, which contribute to weakening the bond between dermis and epidermis of extrinsically age skin. To prevent or improve the skin wrinkles, various strategies, including anti-wrinkle creams, have been pertained to the primary structural components of the dermis, collagen, elastin and GAGs. The aim of study was to evaluate the relationship between long-term application of anti-wrinkle creams and the improvement of facial wrinkle score in participants with various demographic characteristics.This study included five participants with age range of 34-62 years. Information on age and occupation as well as skin condition and types of skin was collected. Arbitrary facial wrinkle score (0 (none) to 10 (maximum)) were examined at baseline and 8 weeks of anti-wrinkle creams treatment. The 8 weeks of treatment showed significantly decreased the degree of wrinkle around the eyes, with mean values (arbitrary unit) of 5.27 unit at baseline and 1.87 unit at 8 weeks of treatment. Similarly, in wrinkle around the mouth, the treatment of anti-wrinkle creams decreased the wrinkle, with mean values of 6.84 unit at baseline and 3.60 unit at 8 weeks of treatment. The results of this study suggest that long-term treatment of anti-wrinkle creams decreases the facial wrinkle in women having various demographic characteristics. Therefore, anti-wrinkle cosmetics is a useful preventive strategy in wrinkle formation in terms of the rejuvenation of the skin primary structural constituents and reduction of inflammatory reaction.

Biography:

Vaishnavi Gowda is currently working in Amrita Institute Of Medical Sciences.

Abstract:

Atypical mycobacteria comprise a heterogeneous non-tuberculous group of acid-fast bacteria involving the skin. The aim of our study was to describe the clinical and pathological features and species profile of atypical mycobacteria with a special mention to treatment response. A retrospective-record based study of patients attending our hospital over the past 5-years was carried out. Of the 3,45,456 patients 33 cases (19 male, 14 female) of atypical mycobacterial cutaneous infections were diagnosed. Patients’ age ranged from 21-75 years and average duration of lesions was 15 months. The diagnosis was proved by direct smear (6.5%), skin biopsy (20.9%), tissue culture (47.8%) and polymerase chain reaction (24.8%). Gene xpert was also carried out in a few cases. All biopsies revealed granulomatous inflammation. The most common organism isolated was Mycobacterium marinum(84.8%) ,with the upper limb being the commonest site. Other species isolated included Mycobacterium fortuitum(10.9%) and Mycobacterium kansasii(4.3%). 32 patients received treatment and 31 responded. 26 patients were treated with oral tetracyclines. Duration of treatment ranged from 8 to 54 weeks. Cutaneous atypical mycobacterial infections are showing a rising trend with Mycobacterium marinum showing highest prevalence. Newer technologies like polymerase chain reaction and gene xpert provide a rapid and sensitive method to improve the diagnosis. Tetracycline group of antibiotics, especially minocycline is effective in cases caused by Mycobacterium marinum. Combination chemotherapy may be a better choice for infections caused by other species.

Biography:

Dr. Yan Li is attending physician of Department of Dermatology in Beijing Friendship Hospital, Capital Medical University. Research focus in dermatology and contact allergy, cosmetology laser, immunological dermatology. She was the member of Medical cosmetology of China Society of Integrated Traditional Chinese and Western Medicine. Contributing Editor of China Clinical physicians of Chinese Medicine Association. She was graduated from Peking university health science center and received Doctor of Medicine in 2009. She has published more than 30 papers in reputed journals

Abstract:

The aim of the study was to investigate the efficacy and safety of halometasone cream to treat chronic generalized eczema and the effects of halometasone cream on serum cortisol (COR) levels. Sixty consecutive outpatients diagnosed with chronic generalized eczema between January and April 2017 were included and divided into groups A, B, and C with a lesion area of 30%-40%, 41%-50%, and 51%-60%, respectively. Groups A, B, and C were treated with halometasone cream with a daily dose of 15 g, 20 g, and 30 g for 7-14 days, respectively. Ten patients were randomly selected from each group for serum COR measurement at days 0, 7, and 14. On day 14, group B had significantly higher cure rate (47.1%) than groups A (17.9%) and C (13.3%) and significantly higher effectiveness rate (82.4%) than group C (40.0%) (all P < 0.05). Serum COR levels were not affected in group A but were reduced significantly in groups B and C on days 7 and 14 (all P < 0.05). No adverse reaction was observed. Halometasone cream appeared to relieve chronic generalized eczema effectively and safely. High dosage (≥20 g daily for 14 days) may temporarily reduce endogenous COR production substantially, although it may be more effective.

Biography:

Dr. WeiXu is Vice physician of Department of Dermatology in Beijing Friendship Hospital. Research focus in dermatology and contact allergy. She was the Youth deputy of Standing Committee of Dermotology Branch of Chinese Medicine Association. Contributing Editor of  China Clinical physicians of Chinese Medicine Association,  Specialist of the qualification of foreign physician who want to practice  at Beijing.  She was graduated from Capital Medical University and received Bachelor of Medicine degree in 1991. Graduated from Capital Medical University and received Master of Medicine, Major in Dermatology in 2004. She got a training of cosmetology laser medcine in 1997 at HongKong. From 2005 to 2006，she went to University of North Carolina at Chapel Hill, UNC ,USA as a visiting scholar for 1 year.
 

Abstract:

This multi-center, 1: 1randomized, double-blind, placebo-controlled study aimed to evaluate the efficacy and safety of the traditional Chinese medicine oral compound glycyrrhizin (OCG) for adult chronic eczema. Methods: A total of 199 patients were equally randomized to the treated group receiving OCG capsules 3 times daily 75mg/time and mometasone furoate 0.1% ointment once daily for 28 days and the placebo group receiving placebo and the topical cream. The eczema area and severity index (EASI) score, the Investigator’s Global Assessment (IGA) score, and visual analogue scale score of itching were evaluated. Results: On day 28 of the treatment, compared with the placebo group, the treated group showed significantly greater extent of reductions in the absolute EASI (-7.39±1.71 vs. -6.64±1.75, P=0.003) and IGA (-2.63 ± 0.75 vs. -2.34±0.70, P<0.05) from the corresponding baselines and had significantly higher proportions of patients achieving EASI 50 (96.8% vs. 87.9%, P=0.021) and EASI 75 (47.9% vs. 21.2%, P<0.001), patients achieving IGA scores of clear (0) or almost clear (1) on day 28 (93.5% vs. 79.4%, P=0.005), and patients showing pruritus attenuation ( 94.7% vs. 83.8%, P=0.016). The treated group showed significantly less recurrence than the placebo group (3.19% vs. 12.12%, P=0.021). Adverse events occurred in 11 patients including 3 in the placebo group (3.0%) and 8 in the treated group (8.5%, P>0.05). Conclusion: OCG capsules combined with topical cream mometasone furoate 0.1% ointment is an effective and safe therapy for adult chronic eczema. Compound glycyrrhizin could be a promising steroid sparing agent for clinical application.

Biography:

WooKoung Lee is currently working in Root Hair Transplantation Center.

Abstract:

Follicular unit extraction has many advantages which is minimal scar, quicker recovery time but definitely have disadvantages as well. One of them include potential for high hair follicle transection rate. The disadvantage is mostly due to blind harvesting technique. Thus we had been looking for imaging methods which make visible technique possible. One of themis the ultrasound scanner which is 22MHz in frequency and shows structures within the dermis. Through it we found out that there were angle differences between hair shaft out of the skin and hair follicle in the occipital scalp. The results were in 20.8-40.3 degree range and 12.8 degree of average. In addition there were significance differences in the average follicle angle depending on the area of occipital region. Therefore we employed it’s data in order to reduce transection rate for graft. But despite ultrasound’s great ability, we was not able to harvest the grafts simultaneously while seeing the hair follicle. So we were searching for something to be capable of resolving the problem and lights gave us good idea. We made the first attempt with the NIR(one kind of lights which is 700-2500nm in wavelength). We were able to identify the hair follicles, but felt a need for further improvement. The most suitable amount of melanin to be observed in hair follicles was 640 nm red visible. We were able to identify hair follicles using 640nm red visible light with PL filter. As a result, we can harvest the grafts while looking at the hair follicles through the monitor simultaneously. While harvesting the hair follicle, we always have potential for transection of it when just depend on blind technique. We have been making much effort to lower transection rate of the follicle and at last we found out Follicoscope and ultrasound scanner. They consequently make visible technique possible. Sincerely I hope that you will provide a chance to demonstrate these equipments to participants.

Biography:

Renni Yuniati is currently doing her research at Leprosy.

Abstract:

Leprosy remains an important health problem in a number of regions and still a public health problem in Indonesia because leprosy generally manifest as neurodegenerative disorder which may lead to permanen disability, morbidity, and social stigmata. Early detection of infection, followed by effective treatment, is critical to reduce disease progression. New sensitive and specific tools for early detection of infection will be a critical component of an effective leprosy elimination campaign. Diagnosis is made by recognizing clinical signs and symptoms, but few clinicians are able to confidently identify these. Simple tests to facilitate referral to leprosy experts are not widely available, and the correct diagnosis of leprosy is often delayed. Indonesia have many research about prevalence of subclinical leprosy in population who live with leprosy patients or contact person and hospital employee in order to determine the rate of transmission and initiate early treatment for those with subclinical disease as well as providing data for future research. The leprosy status of the sample was evaluated using IgM anti-PGL-1 in the serum.

Biography:

Abstract:

Trophic ulcers secondary to leprosy pose a great stigma to the patients and remain a challenge to the treating dermatologists. The discovery of Platelet Rich Fibrin clot (PRF) with its favourable role in wound healing is a boon for the patients. PRF introduces the growth factors directly into the wound and aids in rapid healing. There has been less study performed for its use in trophic ulcers in hansen’s disease so our study brings out the use PRF in treating non healing ulcers in hansens disease. 5 patients (50%) showed complete healing, in 4 patients (40%) there was marked reduction in wound size and 1 patient (10%) lost to follow up. Mean healing time of ulcer is 5 weeks. PRF therapy leads to faster rate of induction of granulation tissue with rapid healing. It is a simple, safe and cost effective opd procedure, albeit requiring an optimal set-up and expertise. More sample size will be required for definitive results.