Edileia Bagatin
Federal University of Sao Paulo, Brazil
Title: Oral antioxidants and nutraceuticals for skin aging control: a critical approach
Biography
Biography: Edileia Bagatin
Abstract
Antioxidants derived from plant extracts have been extensively studied in vitro. Based in the experimental results they are proposed as beneficial oral and topical strategy to control, in vivo, the oxidative stress which is the main pathogenic factor in skin aging, particularly photoaging. However, a paucity of randomized and controlled clinical trials are available to assure the same effects. In addition, some harmful events have been reported. Regarding nutraceuticals, the bioactive peptides of collagen or hydrolyzed collagen (HC) has been suggested as an option to restore dermal collagen content. But there is no evidence about their role as preventive or therapeutic measure and when the supplementation should be initiated. In this lecture results of our in vivo studies about clinical use of oral lycopene to prevent skin damage caused by UVB and the supplementation with HC, in menopaused women, to increase dermal collagen, will be presented.